姓名 | 王云峰 |
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职称 | 教授，主任医师 | |
导师资格 | 硕士研究生导师 | |
学科专业 | 医学技术 | |
联系方式 | E-mail：yunfengwang@fudan.edu.cn | |
一、个人简介 王云峰于2006-2009年在复旦大学和美国Emory University攻读联合培养博士研究生，毕业后就职于复旦大学附属眼耳鼻喉科医院，现担任耳鼻喉科副主任、听力障碍诊治中心主任、综合耳鼻喉科主任、耳鼻咽喉科学博士生导师，长期从事听觉障碍相关临床工作及耳鸣耳聋发病机制和诊疗相关研究，目前主持国家自然科学基金面上项目、上海市“科技创新行动计划”、复旦大学医工结合重点项目等多项课题，受上海市“医苑新星”杰出青年医学人才和复旦大学“卓学计划”人才项目资助，2023年被聘为学院硕士生导师，指导临床听力学相关医学技术研究。 | ||
二、主要学习与工作经历 学习经历： 2006/09 – 2009/06 复旦大学，耳鼻咽喉科学，博士 2008/09 – 2009/06 Emory University，耳鼻咽喉科学，联合培养博士 工作经历： 2009/07 – 至今 复旦大学附属眼耳鼻喉科医院，博导 耳鼻喉科副主任 听力障碍诊治中心主任 综合耳鼻喉科主任 | ||
三、主要科研工作与成绩 科研项目： 1、国家自然科学基金面上项目，81570919，胚胎期干预Cx26条件基因敲除小鼠治疗感音神经性耳聋的研究，2016-2019 2、国家自然科学基金面上项目，82071043，ErbB4/Atoh1信号通路在耳蜗毛细胞发育中的作用及其机制研究，2021-2024 3、国家自然科学基金面上项目，82271167，AQP4对缝隙连接蛋白和内淋巴电位水平的调控在耳蜗毛细胞存活中的作用机制研究，2023-2026 4、上海市“科技创新行动计划”，22JC1403700，脂双层内仿生通道蛋白的组装及其生物活性研究，2022-2025 5、复旦大学医工结合重点项目，yg2022-9，基于神经网络算法的助听器验配专家系统开发，2021-2024 研究成果： 1、Chen, H., Tan, W., Li, J., Guan, P., Wu, L., Yan, B., Li, J., and Wang, Y. (2022). Adaptive Cross Entropy for ultrasmall object detection in Computed Tomography with noisy labels. COMPUT BIOL MED 147, 105763. 2、Cheng, Y., Tang, B., Zhang, G., An, P., Sun, Y., Gao, M., Zhang, Y., Shan, Y., Zhang, J., and Liu, Q., et al. (2022). Degraded cortical temporal processing in the valproic acid-induced rat model of autism. NEUROPHARMACOLOGY 209, 109000. 3、Fan, T., Xiang, M.Y., Li, Y., Gong, J.M., Wu, T., Wang, Y., Xu, J., Wang, Y.F., and Li, J. (2022). Effect of Electrode Insertion Angle on Cochlear Implantation Outcomes in Adult and Children Patients with Sensorineural Hearing Loss. OXID MED CELL LONGEV 2022, 9914716. 4、Fan, T., Xiang, M.Y., Zhou, R.Q., Li, W., Wang, L.Q., Guan, P.F., Li, G.L., Wang, Y.F., and Li, J. (2022). Effect of Sodium Salicylate on Calcium Currents and Exocytosis in Cochlear Inner Hair Cells: Implications for Tinnitus Generation. NEUROSCI BULL 38, 69-80. 5、Tan, W., Guan, P., Wu, L., Chen, H., Li, J., Ling, Y., Fan, T., Wang, Y., Li, J., and Yan, B. (2021). The use of explainable artificial intelligence to explore types of fenestral otosclerosis misdiagnosed when using temporal bone high-resolution computed tomography. Ann Transl Med 9, 969. 6、Yan, Z.J., Wang, D., Ye, Z., Fan, T., Wu, G., Deng, L., Yang, L., Li, B., Liu, J., and Ma, T., et al. (2020). Artificial Aquaporin That Restores Wound Healing of Impaired Cells. J AM CHEM SOC 142, 15638-15643. 7、Qi, J., Zhang, L., Tan, F., Liu, Y., Chu, C., Zhu, W., Wang, Y., Qi, Z., and Chai, R. (2020). Espin distribution as revealed by super-resolution microscopy of stereocilia. AM J TRANSL RES 12, 130-141. 8、Li, C., Wang, Y., Wang, G., Lu, Y., He, S., Sun, Y., and Liu, Z. (2020). Fate-mapping analysis using Rorb-IRES-Cre reveals apical-to-basal gradient of Rorb expression in mouse cochlea. Dev Dyn 249, 173-186. 9、He, Y., Li, W., Zheng, Z., Zhao, L., Li, W., Wang, Y., and Li, H. (2020). Inhibition of Protein arginine methyltransferase 6 reduces reactive oxygen species production and attenuates aminoglycoside- and cisplatin-induced hair cell death. THERANOSTICS 10, 133-150. 10、Zheng, Z., Wang, Y., Yu, H., Li, W., Wu, J., Cai, C., and He, Y. (2020). Salvianolic acid B inhibits ototoxic drug-induced ototoxicity by suppression of the mitochondrial apoptosis pathway. J CELL MOL MED 24, 6883-6897. 11、Waqas, M., Us-Salam, I., Bibi, Z., Wang, Y., Li, H., Zhu, Z., and He, S. (2020). Stem Cell-Based Therapeutic Approaches to Restore Sensorineural Hearing Loss in Mammals. NEURAL PLAST 2020, 8829660. 12、Zeng, S., Ni, W., Jiang, H., You, D., Wang, J., Lu, X., Liu, L., Yu, H., Wu, J., and Chen, F., et al. (2020). Toxic Effects of 3,3'-Iminodipropionitrile on Vestibular System in Adult C57BL/6J Mice In Vivo. NEURAL PLAST 2020, 1823454. 13、Cheng, C., Wang, Y., Guo, L., Lu, X., Zhu, W., Muhammad, W., Zhang, L., Lu, L., Gao, J., and Tang, M., et al. (2019). Age-related transcriptome changes in Sox2+ supporting cells in the mouse cochlea. STEM CELL RES THER 10, 365. 14、Zhang, Y., Li, W., He, Z., Wang, Y., Shao, B., Cheng, C., Zhang, S., Tang, M., Qian, X., and Kong, W., et al. (2019). Pre-treatment With Fasudil Prevents Neomycin-Induced Hair Cell Damage by Reducing the Accumulation of Reactive Oxygen Species. FRONT MOL NEUROSCI 12, 264. 15、Wu, L., Yu, H., Zhou, R., Luo, J., Zhao, J., Li, Y., Wang, K., Wang, Y., and Li, H. (2019). Probe-based confocal laser endomicroscopy for diagnosis of nasopharyngeal carcinoma in vivo. LARYNGOSCOPE 129, 897-902. 16、Xia, L., Zhu, W., Wang, Y., He, S., and Chai, R. (2019). Regulation of Neural Stem Cell Proliferation and Differentiation by Graphene-Based Biomaterials. NEURAL PLAST 2019, 3608386. 17、Chen, B., Wang, Y., Geng, M., Lin, X., and Tang, W. (2018). Localization of Glucose Transporter 10 to Hair Cells' Cuticular Plate in the Mouse Inner Ear. BIOMED RES INT 2018, 7817453. 18、Liu, S., Wang, Y., Lu, Y., Li, W., Liu, W., Ma, J., Sun, F., Li, M., Chen, Z.Y., Su, K., and Li, W. (2018). The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns. NEURAL PLAST 2018, 7513258. 19、王云峰, 颜波, 李健, 李吉春, 谭伟敏. 一种基于颞骨CT平扫影像的左右耳区域分割方法. 发明专利. 202010124604.2 20、王云峰, 颜波, 李健, 谭伟敏, 管鹏飞, 陈赫丹, 吴灵捷, 李吉春. 基于小目标检测神经网络的耳硬化病灶检测及诊断系统. 发明专利. 202011263682.7 21、颜波, 王云峰, 李健, 谭伟敏, 陈赫丹. 基于目标检测神经网络的耳硬化病灶检测及诊断系统. 发明专利. 202010784988.0 22、王云峰, 周韧, 倪玉苏, 吴灵捷. 一种耳蜗植入手术中的皮瓣牵开器. 实用新型专利. 201721159402.1 | ||
四、主要社会学术团体兼职 1、中国听力医学发展基金会儿童听力保健专家委员会副主任委员 2、中国电子音响行业协会助听行业分会副主任委员 3、中华医学会耳鼻喉科分会听力学组委员 4、上海市医学会听力与前庭医学专科分会委员兼秘书 5、全国防聋治聋及数字诊疗技术推广联盟专业委员会委员兼秘书 | ||
五、主要研究方向 1、听觉医学诊疗与耳聋耳鸣发病机制研究 | ||
