三、主要科研工作与成绩 迄今为止，先后主持3项国家级项目，3项上海市科研项目。在权威杂志上发表SCI论45篇，第一作者和通讯作者14篇，包括Nature Communications (IF=17.69), Pharmacol Res(IF=10.33), J Med Chem(IF= 8.03)，J Bone Miner Res (IF=6.39)等。 代表性论文： (1) Zhenxi Li; Xinghai Yang; Ruifeng Fu; Zhipeng Wu; Shengzhao Xu; Jian Jiao; Ming Qian; Long Zhang; Chunbiao Wu; Tianying Xie; Jiqiang Yao; Zhixiang Wu; Wenjun Li; Guoli Ma; Yu You; Yihua Chen; Han-kun Zhang; Yiyun Cheng; Xiaolong Tang; Pengfei Wu; Gewei Lian; Haifeng Wei; Jian Zhao; Jianrong Xu; Lianzhong Ai; Stefan Siwko; Yue Wang; Jin Ding; Gaojie Song; Jian Luo; Mingyao Liu; Jianru Xiao ; Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src, Nature Communications, 2024, 15(1): 1500 (期刊论文) ( 本人标注: 共同第一作者, 唯一通讯作者 ) (2) Zhenxi Li; Jinping Huang; Fanhua Wang; Wenjun Li; Xian Wu; Chenglong Zhao; Jian Zhao; Haifeng Wei; Zhipeng Wu; Ming Qian; Peng Sun; Liang He; Yunyun Jin; Jie Tang; Wenwei Qiu; Stefan Siwko; Mingyao Liu; Jian Luo; Jianru Xiao ; Dual Targeting of Bile Acid Receptor-1 (TGR5) and Farnesoid X Receptor (FXR) Prevents Estrogen-Dependent Bone Loss in Mice, Journal of Bone and Mineral Research, 2019, 34(4): 765-776 (期刊论文) ( 本人标注: 唯一第一作者 ) (3) Zhenxi Li; Jing Liu; Hiroyuki Inuzuka; Wenyi Wei ; Functional analysis of the emerging roles for the KISS1/KISS1R signaling pathway in cancer metastasis, Journal of Genetics and Genomics, 2021, 21(00339-8): S1673-8527 (期刊论文) ( 本人标注: 唯一第一作者 ) (4) Dongsheng Wang; Zhixiang Wu; Chenglong Zhao; Xinghai Yang; Haifeng Wei; Mingyao Liu; Jian Zhao; Ming Qian; Zhenxi Li; Jianru Xiao ; KP-10/Gpr54 attenuates rheumatic arthritis through inactivating NF-κB and MAPK signaling in macrophages., Pharmacological Research, 2021, 105496 (期刊论文) ( 本人标注: 共同通讯作者 ) (5) Chenglong Zhao; Xiaopan Cai; Yao Wang; Dongsheng Wang; Ting Wang; Haiyi Gong; Haitao Sun; Qi Jia; Wang Zhou; Zhipeng Wu; Zhenxi Li; Jianru Xiao ; NAT1 promotes osteolytic metastasis in luminal breast cancer by regulating the bone metastatic niche via NF-kappa B/IL-1B signaling pathway, American Journal of Cancer Research, 2020, 10(8): 2464-2479 (期刊论文) ( 本人标注:共同通讯作者 ) | 
